In a period of rapid NHS reform and organisational flux, many within the pharmaceutical sector and wider health system were struggling to understand shifting priorities, operational pressures and the implications for collaboration. Nonfed was created as a new, bottom-up forum to cut through this complexity by convening the “doers” across health and care for an open, engaging exploration of what these changes mean. Against a backdrop of the Three Big Shifts, it sought to re-centre patients in strategic conversations and to highlight how pharma’s value propositions must evolve to remain relevant.

The event was delivered virtually to ensure wide access that traditional events don’t deliver, structured around interactive sessions, debate and thought experiments. Themes included policy updates, mental wellbeing and personal resilience, patient-centric approaches, and the enablers and blockers of collaboration. Specific provocations challenged participants to consider how providers will organise in the future, how medicines will be positioned in increasingly constrained budgets, and where partnership opportunities may emerge as Integrated Care Boards (ICBs) reshape. Insights were gathered from multi-sector participants, ensuring a balanced and practical perspective on these issues.

The sessions surfaced a set of key challenges and opportunities for pharma: the urgent need to align propositions with patient priorities, the reality that medicines may be deprioritised in financial decision-making, and the difficulty of forging partnerships amidst workforce and system strain. Equally, participants identified opportunities in building clearer evidence of system-level value, reframing digital solutions as enablers of prevention, and working with providers as they adapt to new competitive and collaborative dynamics. The result is a sharper understanding of how pharma can refine its value propositions to support system transformation while maintaining patient focus.